Wearable hand devices span a spectrum of rigid exoskeletons to soft wearables, each with their advantages and limitations. To tackle future applications, hand wearables must leverage advantages of both rigid and soft systems. However, the effects of specific design choices on wearable device performance are still an open area of research. In this project, I propose a simulation-based framework that uses a model in Simscape Multibody to study how design parameters affect pHRI performance of wearable hand devices. Simulation results are validated with the Maestro hand exoskeleton to confirm that trends translate to the real world. Through this approach, we can rapidly explore the broad design space for wearable hand devices in simulation to inform prototyping for real-world implementation.